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KMID : 0356619930080020221
Journal of Korean Society of Endocrinology
1993 Volume.8 No. 2 p.221 ~ p.224
A Case of Myopathy Associated with Hyperthyroidism
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Abstract
ABSTRACT
@EN Graves' disease was associated with a variety of muscle abnormalities, from myalgia to severe myasthenia gravis. There were several reports of myopathy associated with autoimmune thyroiditis or Graves' disease. Polymyositis, however, has been
reported in very few cases, especially only one case was reported in Korea. Now, we present a case of myopathy associated with Graves' disease.
53-year-old man developed idiopathic polymyositis during treatment of Graves disease with propylthiouracil. He developed proximal muscle weakness during treatment of Graves' disease. His serum creatine phosphokinase level and other muscle enzyme
level
were within normal limit. But muscle biopsy and the clinical course of illness were consistent with idiopathic polymyositis. His symptoms were much improved during the treatment with prophylthiouracil and corticosteroids.
Muscular weakness is common accompaniment of hyperthyroidism or thyrotoxicosis. The exact relation between the hyperthyroidism and polymyositis is still unknown. (J Kor Soc Endocrinol 8:221~224, 1993)
KEYWORD
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